TFS SDK - Getting to grips with the programmatic world of TFS
http://blogs.msdn.com/bharry/archive/2008/07/09/working-on-tfs-sdk-improvements.aspx is your first stop before you start the journey or programmatic access to TFS. Brian's blog documents an exceptional sample program that demonstrates the use of the VsSDK, which you can find here, with simple and clear code examples.
